Floods are a widespread and damaging natural phenomenon that causes harm to human lives, resources, property and has agricultural, eco-environmental, and economic impacts. Therefore, it is crucial to perform flood susceptibility mapping (FSM) to identify susceptible zones to mitigate and reduce damage. This study assessed the damage caused by the 2022 flash flood in Sindh and identified flood-susceptible zones based on the frequency ratio (FR) and analytical hierarchy process (AHP) models. This study enhances the scientific understanding of flash flood impacts across diverse regions and emphasizes the importance of accurate FSM for informed decision-making. The findings provide important informations and are supportive for policymakers, agricultural planners, and stakeholders engaged in flood risk management to mitigate the adverse consequences of flash floods.